At least 13 people were killed on Saturday when a car bomb exploded in a market in the Turkish-controlled city of Tal Abyad in northern Syria, Ankara and the Syrian Observatory for Human Rights said.
"According to preliminary data, 13 civilians were killed and 20 wounded," the Turkish Defense Ministry said.
Turkish troops seized the border town of Tal Abyad in an attack last month on the Kurdish People´s Protection Units (YPG), which Ankara classifies as "terrorist", but has received support from Western countries in fighting the Islamic State (IS).
The Turkish Defense Ministry said in a statement: "We condemn in the strongest terms this inhuman attack committed by terrorists and YPG against innocent civilians in Tel Abyad."
For its part, the Syrian Observatory for Human Rights reported the killing of 14 civilians and members of Syrian opposition factions supported by Ankara, in the explosion, without identifying the perpetrators of the attack.
Ankara announced that its offensive in northeastern Syria, which was halted in the light of agreements with Washington and Moscow to provide for the withdrawal of Kurdish fighters to the south, aims to establish a "safe area" along its border.
During the attack, the Turkish army and the Syrian factions close to it took control of a 120-kilometer-long strip, 30 kilometers wide from Tall Abyad to Ras al-Ain.
Turkish President Recep Tayyip Erdogan said his goal was to move two million Syrian refugees living in Turkey to the planned "safe zone."